The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2014

Filed:

Nov. 25, 1997
Applicants:

Elazar Rabbani, New York, NY (US);

Jannis G. Stavrianopoulos, Bay Shore, NY (US);

James J. Donegan, Long Beach, NY (US);

Dakai Liu, Bethpage, NY (US);

Norman E. Kelker, New York, NY (US);

Dean L. Engelhardt, New York, NY (US);

Inventors:

Elazar Rabbani, New York, NY (US);

Jannis G. Stavrianopoulos, Bay Shore, NY (US);

James J. Donegan, Long Beach, NY (US);

Dakai Liu, Bethpage, NY (US);

Norman E. Kelker, New York, NY (US);

Dean L. Engelhardt, New York, NY (US);

Assignee:

Enzo Biochem, Inc., Farmingdale, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01); C12Q 1/68 (2006.01); C12N 9/12 (2006.01); C12Q 1/70 (2006.01); C07K 14/005 (2006.01); C07K 14/62 (2006.01); C12N 15/87 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1132 (2013.01); C12Q 2525/307 (2013.01); C12Q 2525/301 (2013.01); C12Q 1/6897 (2013.01); C12N 9/1247 (2013.01); C12Q 1/703 (2013.01); C07K 14/005 (2013.01); C12N 2740/16322 (2013.01); C07K 14/62 (2013.01); C12N 15/87 (2013.01);
Abstract

The present invention provides an array of compositions useful for effecting and/or exhibiting changes in biological functioning and processing within cells and in biological systems containing such cells. In effect, these compositions combine chemical modifications and/or ligand additions with biological functions. The chemical modifications and/or ligand additions provide additional characteristics to the compositions without interfering substantially with their biological function. Such additional characteristics include nuclease resistance, targeting specific cells or specific cell receptors localizing to specific sites within cells and augmenting interactions between the compositions and target cells of interest as well as decreasing such interactions when desired. Also provided by the present invention are processes and kits.


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