The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2014

Filed:

Oct. 29, 2010
Applicants:

Yusuke Tanigawara, Tokyo, JP;

Tetsuya Suzuki, Tokyo, JP;

Akito Nishimuta, Tokyo, JP;

Shinji Sugimoto, Tokyo, JP;

Yoshiaki Igarashi, Tokyo, JP;

Inventors:

Yusuke Tanigawara, Tokyo, JP;

Tetsuya Suzuki, Tokyo, JP;

Akito Nishimuta, Tokyo, JP;

Shinji Sugimoto, Tokyo, JP;

Yoshiaki Igarashi, Tokyo, JP;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4375 (2006.01); A61P 35/00 (2006.01); A61K 31/4745 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01); G01N 33/18 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4745 (2013.01); G01N 33/5011 (2013.01); G01N 33/574 (2013.01); G01N 33/18 (2013.01);
Abstract

To provide a marker for determining sensitivity of a patient to an anti-cancer agent, and novel cancer therapeutic means employing the marker. The marker for determining sensitivity to an anti-cancer agent is formed of one or more substances selected from the group consisting of a substance or a fragment thereof detected as an anion at m/z of 149.05 to 149.06, a substance or a fragment thereof detected as an anion at m/z of 152.99 to 153.00, a substance or a fragment thereof detected as a cation at m/z of 724.34 to 724.35, the peaks being determined by means of a mass spectrometer, glycerol 3-phosphate, dihydrobiopterin, GABA, lactic acid, asparagine, aspartic acid, 2-methylbutyroylcarnitine, 1-methyladenosine, and glutathione, and a substance involved in a metabolic pathway of any of these substances.


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