The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2014
Filed:
Mar. 29, 2010
Applicants:
David Davido, Lawrence, KS (US);
William Halford, Springfield, IL (US);
Inventors:
David Davido, Lawrence, KS (US);
William Halford, Springfield, IL (US);
Assignees:
University of Kansas, Lawrence, KS (US);
Southern Illinois University, Springfield, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C12N 7/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
A mutant herpesvirus that has a mutated gene that encodes a mutant infected cell protein 0 (ICP0) can be used in therapeutic methods as well as in diagnostics and research experiments. The encoded mutant ICP0 protein can be altered in one or more regions of ICP0 that are substantially conserved between two or more herpesviruses and/or within a phosphorylation region. The mutant herpesvirus can be substantially avirulent and immunogenic.