The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2014
Filed:
Apr. 17, 2009
Richard W. Heidebrecht, Brookline, MA (US);
Chaomin LI, Boston, MA (US);
Benito Munoz, Newtonville, MA (US);
Andrew Rosenau, Philadelphia, PA (US);
Laura M. Surdi, Collegeville, PA (US);
Paul Tempest, Brookline, MA (US);
Richard W. Heidebrecht, Brookline, MA (US);
Chaomin Li, Boston, MA (US);
Benito Munoz, Newtonville, MA (US);
Andrew Rosenau, Philadelphia, PA (US);
Laura M. Surdi, Collegeville, PA (US);
Paul Tempest, Brookline, MA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The invention encompasses a novel class of cyclobutyl sulfone derivatives which inhibit the processing of APP by the putative γ-secretase while sparing Notch signaling pathway, and thus are useful in the treatment or prevention of Alzheimer's disease without the development of Notch inhibition mediated gastrointestinal issues. Pharmaceutical compositions and methods of use are also included.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile