The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2014
Filed:
Feb. 07, 2013
Applicant:
Arqule, Inc., Woburn, MA (US);
Inventors:
Chiang J. Li, West Roxbury, MA (US);
Mark A. Ashwell, Carlisle, MA (US);
Jason Hill, Auburndale, MA (US);
Magdi M. Moussa, Malden, MA (US);
Neru Munshi, Burlington, MA (US);
Assignee:
ArQule, Inc., Woburn, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); A61K 31/473 (2006.01); A61K 31/551 (2006.01); A61K 31/661 (2006.01); C07D 471/06 (2006.01); C07D 487/06 (2006.01); C07F 9/12 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to pyrroloquinolinyl-pyrrolidine-2,5-dione compounds in combination with chemotherapeutic agents. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the present invention and also administering a effective amount of a chemotherapeutic agent.