The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2014

Filed:

Jan. 28, 2013
Applicant:

Vertex Pharmaceuticals Incorporated, Cambridge, MA (US);

Inventors:

Beili Zhang, San Diego, CA (US);

Mariusz Krawiec, Marlborough, MA (US);

Brian Luisi, Mansfield, MA (US);

Ales Medek, Winchester, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/04 (2006.01); A61K 31/4748 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4748 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention relates to substantially crystalline and solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide (Form A-HCl, Form B, Form B-HCl, or any combination of these forms), pharmaceutical compositions thereof, and methods of treatment therewith.


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