The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2014
Filed:
Feb. 28, 2008
Tadashi Fujii, Tokyo, JP;
Atsushi Ochiai, Tokyo, JP;
Masashi Ito, Tokyo, JP;
Hiroki Kabumoto, Tokyo, JP;
Yoshikazu Fujii, Tokyo, JP;
Kazuhiro Machida, Tokyo, JP;
Tadashi Fujii, Tokyo, JP;
Atsushi Ochiai, Tokyo, JP;
Masashi Ito, Tokyo, JP;
Hiroki Kabumoto, Tokyo, JP;
Yoshikazu Fujii, Tokyo, JP;
Kazuhiro Machida, Tokyo, JP;
Microbiopharm Japan Co., Ltd, Tokyo, JP;
Abstract
Disclosed is a means for improving the poor conversion efficiency in a conventional bioconversion system using a transformant which is given by introducing a gene originated from xerogenic organisms. A transformant is prepared by using a host which is defective in a gene encoding a multidrug efflux protein and introducing a gene originated from xerogenic organisms. Use of the transformant results in much effective microbial conversion of a hydrophobic or amphipathic substrate compound into a desired compound. In case, anis used as the host, the gene encoding a multidrug efflux protein to be defective may be tolC, acrA, acrB and the like.