The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2014
Filed:
Nov. 17, 2009
Anil K. Sood, Pearland, TX (US);
Andras G. Lacko, Ft. Worth, TX (US);
Gabriel Lopez-berestein, Bellaire, TX (US);
Lingegowda S. Mangala, Webster, TX (US);
Walter J. Mcconathy, Midland, TX (US);
Laszlo Prokai, Mansfield, TX (US);
Maya P. Nair, Coppell, TX (US);
Anil K. Sood, Pearland, TX (US);
Andras G. Lacko, Ft. Worth, TX (US);
Gabriel Lopez-Berestein, Bellaire, TX (US);
Lingegowda S. Mangala, Webster, TX (US);
Walter J. McConathy, Midland, TX (US);
Laszlo Prokai, Mansfield, TX (US);
Maya P. Nair, Coppell, TX (US);
University of North Texas Health Science Center at Fort Worth, Fort Worth, TX (US);
The Board of Regents, The University of Texas System, Austin, TX (US);
Abstract
Disclosed are high density lipoprotein-nucleic acid particles, wherein the particles include (a) an apolipoprotein; (b) a nucleic acid component comprising a therapeutic nucleic acid segment; and (c) a polypeptide comprising a positively charged region, wherein the positively-charged region of the polypeptide associates with the nucleic acid component. Also disclosed are pharmaceutical compositions that include a) an apolipoprotein; (b) a nucleic acid component comprising a therapeutic nucleic acid segment; and (c) a polypeptide comprising a positively charged region. Methods that concern the particles and pharmaceutical compositions of the present invention are also set forth, as well as kits.