The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2014
Filed:
Apr. 21, 2006
Nicolaas Petrus Willard, Eindhoven, NL;
Rene Theodorus Wegh, Eindhoven, NL;
Jeroen Alphons Pikkemaat, Eindhoven, NL;
Holger Gruell, Eindhoven, NL;
Nicolaas Petrus Willard, Eindhoven, NL;
Rene Theodorus Wegh, Eindhoven, NL;
Jeroen Alphons Pikkemaat, Eindhoven, NL;
Holger Gruell, Eindhoven, NL;
Koninklijke Philips N.V., Eindhoven, NL;
Abstract
The invention provides MRI contrast agents which provide a high sensitivity and which have an optimised body retention time. These agents enable the mapping of the local pH, temperature, oxygen concentration or other metabolites in a patient's body by the use of Chemical Exchange Saturation Transfer (CEST). Particularly pH and temperature mapping are useful for the detection of small cancer lesions and localized inflammation respectively.