The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 2014

Filed:

Feb. 28, 2011
Applicants:

Je-tae Woo, Aichi, JP;

Ayaka Hibino, Aichi, JP;

Takayuki Yonezawa, Aichi, JP;

Midori Asai, Aichi, JP;

Toshiaki Teruya, Aichi, JP;

Byung-yoon Cha, Aichi, JP;

Kazuo Nagai, Aichi, JP;

Inventors:

Je-Tae Woo, Aichi, JP;

Ayaka Hibino, Aichi, JP;

Takayuki Yonezawa, Aichi, JP;

Midori Asai, Aichi, JP;

Toshiaki Teruya, Aichi, JP;

Byung-Yoon Cha, Aichi, JP;

Kazuo Nagai, Aichi, JP;

Assignee:

Erina Co., Inc., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 311/00 (2006.01); C07D 311/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Agents or pharmaceutical compositions for promoting osteoblast differentiation include purified auraptene or coumarin analogs thereof represented by the following formula 1: wherein R1 represents a hydrogen, a hydroxy, a methoxy, a methyl, an ethyl, a propyl, a carboxyl, a carboxymethyl, or a carboxyethyl; R2 represents a hydrogen, a hydroxy, a methoxy, a methyl, an ethyl, a propyl, a carboxyl, a carboxymethyl, a carboxyethyl or a coumarinyl; R3 represents a hydrogen, a hydroxy, a methoxy, a methyl, an ethyl, a propyl, a carboxyl, a carboxymethyl or a carboxyethyl; and R4 represents a hydrogen, a C-Cliner or branched alkyl, an alkenyl, an alkadienyl or an alkatrienyl.


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