The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2014
Filed:
Oct. 27, 2010
Mario R. Mautino, Ankeny, IA (US);
Sanjeev Kumar, Ames, IA (US);
Firoz Jaipuri, Ames, IA (US);
Jesse Waldo, Huxley, IA (US);
Tanay Kesharwani, Lake Katrine, NY (US);
Mario R. Mautino, Ankeny, IA (US);
Sanjeev Kumar, Ames, IA (US);
Firoz Jaipuri, Ames, IA (US);
Jesse Waldo, Huxley, IA (US);
Tanay Kesharwani, Lake Katrine, NY (US);
NewLink Genetics Corporation, Ames, IA (US);
Abstract
Presently provided are IDO inhibitors of general formulae (VII), (VIII) as shown below and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated immunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosupression associated with an infectious disease.