The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 01, 2014

Filed:

Feb. 26, 2008
Applicants:

Douglas S. Clark, Orinda, CA (US);

Timothy Whitehead, Berkeley, CA (US);

Frank T. Robb, Gaithersburg, MD (US);

Pongpan Laksanalamai, Baltimore, MD (US);

Anchalee Jiemjit, Baltimore, MD (US);

Inventors:

Douglas S. Clark, Orinda, CA (US);

Timothy Whitehead, Berkeley, CA (US);

Frank T. Robb, Gaithersburg, MD (US);

Pongpan Laksanalamai, Baltimore, MD (US);

Anchalee Jiemjit, Baltimore, MD (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 1/00 (2006.01); C12N 1/20 (2006.01); C12N 15/74 (2006.01); C12Q 1/02 (2006.01); C12P 21/06 (2006.01); C12P 7/06 (2006.01); C12P 7/16 (2006.01); C07K 1/00 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides methods and compositions for increasing tolerance of microorganisms to toxic agents, such as solvents; and for increasing production of solvents from solvent-generating microorganisms. The methods comprise engineering a microorganism of interest to express a heterologous heat-shock protein/chaperone, e.g., Group II chaperonin or a prefoldin such as γ-prefoldin, where the heterologous protein is from an extremophile, such as an archaean.


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