The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2014
Filed:
Dec. 05, 2011
Applicants:
Masaru Miyagi, Grand Forks, ND (US);
Chandra Sekhar Rao Kadiyala, Grand Forks, ND (US);
Inventors:
Masaru Miyagi, Grand Forks, ND (US);
Chandra sekhar rao Kadiyala, Grand Forks, ND (US);
Assignee:
University of North Dakota, Grand Forks, ND (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 1/00 (2006.01); C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
Abstract
Optimized enzymatic conditions incorporate a single oxygen atom into digested peptides using a peptidase. The incorporation of a single oxygen atom is especially useful for proteolyticO labeling in comparative proteomics. The optimized proteolyticO labeling minimizes the generation of a mixture of isotopic isoforms of the peptides resulting from incorporation of either one or twoO atoms. The outcome is accurate quantification of isotopically labeled peptides.