The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2014
Filed:
Aug. 26, 2011
Melissa D. Bosak, Mount Royal, NJ (US);
Michael W. Bostick, Wilmington, DE (US);
Hongxian He, Wilmington, DE (US);
Seung-pyo Hong, Hockessin, DE (US);
Dana M. Walters Pollak, West Chester, PA (US);
Pamela L. Sharpe, Wilmington, DE (US);
Yehong Jamie Wang, Newark, DE (US);
Zhixiong Xue, Chadds Ford, PA (US);
Narendra S. Yadav, Wilmington, DE (US);
Hongxiang Zhang, Chadds Ford, PA (US);
Quinn Qun Zhu, West Chester, PA (US);
Melissa D. Bosak, Mount Royal, NJ (US);
Michael W. Bostick, Wilmington, DE (US);
Hongxian He, Wilmington, DE (US);
Seung-Pyo Hong, Hockessin, DE (US);
Dana M. Walters Pollak, West Chester, PA (US);
Pamela L. Sharpe, Wilmington, DE (US);
Yehong Jamie Wang, Newark, DE (US);
Zhixiong Xue, Chadds Ford, PA (US);
Narendra S. Yadav, Wilmington, DE (US);
Hongxiang Zhang, Chadds Ford, PA (US);
Quinn Qun Zhu, West Chester, PA (US);
E I du Pont de Nemours and Company, Wilmington, DE (US);
Abstract
Mutant delta-5 desaturases, having the ability to convert dihomo-gamma-linolenic acid [DGLA; 20:3 omega-6] to arachidonic acid [ARA; 20:4 omega-6] and/or eicosatetraenoic acid [ETA; 20:4 omega-3] to eicosapentaenoic acid [EPA; 20:5 omega-3] and possessing at least one mutation within the HPGG (SEQ ID NO:7) motif of the cytochome b-like domain and at least one mutation within the HDASH (SEQ ID NO:8) motif are disclosed. Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding delta-5 desaturases, along with a method of making long chain polyunsaturated fatty acids ['PUFAs'], are also disclosed.