The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2014

Filed:

Jul. 07, 2009
Applicants:

Elena E. Brevnova, Lebanon, NH (US);

Vineet Rajgarhia, Lebanon, NH (US);

Mark Mellon, Grantham, NH (US);

Anne Warner, Lebanon, NH (US);

John Mcbride, Lebanon, NH (US);

Chhayal Gandhi, Lebanon, NH (US);

Erin Wiswall, Danbury, NH (US);

Inventors:

Elena E. Brevnova, Lebanon, NH (US);

Vineet Rajgarhia, Lebanon, NH (US);

Mark Mellon, Grantham, NH (US);

Anne Warner, Lebanon, NH (US);

John McBride, Lebanon, NH (US);

Chhayal Gandhi, Lebanon, NH (US);

Erin Wiswall, Danbury, NH (US);

Assignee:

Mascoma Corporation, Lebanon, NH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast. The cellulases can also be co-expressed in host cells with other cellulases. The expression in such host cells of the termite and termite-associated symbiont cellulases, and variants and combinations thereof, result in yeast with improved cellulosic activity. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.


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