The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2014
Filed:
Oct. 04, 2010
Sanjay Jain, London, GB;
Peter Laing, London, GB;
Gregory Gregoriadis, London, GB;
Dale Howard Hreczuk-hirst, London, GB;
Ioannis Papaioannou, London, GB;
Sanjay Jain, London, GB;
Peter Laing, London, GB;
Gregory Gregoriadis, London, GB;
Dale Howard Hreczuk-Hirst, London, GB;
Ioannis Papaioannou, London, GB;
Lipoxen Technologies Limited, London, GB;
Abstract
Derivatives are synthesized of starting materials, usually polysaccharides, having sialic acid at the reducing terminal end, in which the reducing terminal unit is transformed into an aldehyde group. Where the polysaccharide has a sialic acid unit at the non-reducing end it may be passivated, for instance by converting into hydroxyl-substituted moiety. The derivatives may be reacted with substrates, for instance containing amine or hydrazine groups, to form non-cross-linked polysialylated compounds. The substrates may, for instance, be therapeutically useful drugs peptides or proteins or drug delivery systems.