The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2014
Filed:
Feb. 09, 2011
David J. Squirrell, Salisbury, GB;
Melenie J. Murphy, Salisbury, GB;
Rachel L. Price, Salisbury, GB;
Christopher R. Lowe, Cambridge, GB;
Peter J. White, Cambridge, GB;
Laurence C. Tisi, Cambridge, GB;
James A. H. Murray, Cambridge, GB;
David J. Squirrell, Salisbury, GB;
Melenie J. Murphy, Salisbury, GB;
Rachel L. Price, Salisbury, GB;
Christopher R. Lowe, Cambridge, GB;
Peter J. White, Cambridge, GB;
Laurence C. Tisi, Cambridge, GB;
James A. H. Murray, Cambridge, GB;
Promega Corporation, Madison, WI (US);
Abstract
An isolated recombinant luciferase having luciferase activity. The recombinant luciferase has an amino acid sequence which differs from the wild-type luciferase fromor. In the sequence of the recombinant luciferase, the amino acid residue corresponding to phenylalanine 295 inwild-type luciferase or to leucine 297 inorwild-type luciferases, is mutated compared to the corresponding amino acid which appears in the corresponding wild-type luciferase sequence. The recombinant luciferase has increased thermostability compared to the corresponding wild-type luciferase.