The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2014
Filed:
Sep. 16, 2008
Sitharthan Kamalakaran, Pelham, NY (US);
Robert Lucito, East Meadow, NY (US);
James Bruce Hicks, Lattingtown, NY (US);
Sitharthan Kamalakaran, Pelham, NY (US);
Robert Lucito, East Meadow, NY (US);
James Bruce Hicks, Lattingtown, NY (US);
Koninklijke Philips N.V., Eindhoven, NL;
Cold Spring Harbor Laboratories, Cold Spring Harbor, NY (US);
Abstract
The invention relates to a method for the analysis of ovarian cancer disorders, comprising determining the genomic methylation status of one or more CpG dinucleotides in a sequence selected from the group of sequences according to SEQ ID NO. 1 to 10 and/or SEQ ID NO. 50 to SEQ ID NO. 60. Optionally, additionally following steps are performed, the one or more results from the methylation status test is input into a classifier that is obtained from a Diagnostic Multi Variate Model, calculating a likelihood as to whether the sample is from a normal tissue or an ovarian cancer tissue and/or, calculating an associated p-value for the confidence in the prediction.