The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2013

Filed:

Aug. 11, 2005
Applicants:

Mark A. Ashwell, Carlisle, MA (US);

Manish Tandon, Framingham, MA (US);

Jean-marc Lapierre, Pelham, NH (US);

Yanbin Liu, Acton, MA (US);

Inventors:

Mark A. Ashwell, Carlisle, MA (US);

Manish Tandon, Framingham, MA (US);

Jean-Marc Lapierre, Pelham, NH (US);

Yanbin Liu, Acton, MA (US);

Assignee:

ArQule, Inc., Woburn, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/42 (2006.01); A61K 31/47 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to quinone prodrug compositions and therapeutic methods using such prodrug compositions. Preferably, the quinone compounds of the invention are napthoquinone compounds such as β-lapachone or β-lapachone analogs. The quinone prodrug compositions of the invention exhibit improved solubility, stability, bioavailability, and pharmacokinetic properties, as well as improved plasma half-life in vivo.


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Ashwell, Mark. (2013). Quinone prodrug compositions and methods of use (U.S. Patent No. 8614228). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8614228

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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