The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2013
Filed:
Jul. 20, 2010
Applicants:
Tsafi Pe'ery, Montclair, NJ (US);
Michael B. Mathews, Montclair, NJ (US);
Mainul Hogue, North Arlington, NJ (US);
Hartmut Martin Hanauske-abel, Englewood Cliffs, NJ (US);
Inventors:
Tsafi Pe'ery, Montclair, NJ (US);
Michael B. Mathews, Montclair, NJ (US);
Mainul Hogue, North Arlington, NJ (US);
Hartmut Martin Hanauske-Abel, Englewood Cliffs, NJ (US);
Assignee:
Rutgers the State University of New Jersey, New Brunswick, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 31/426 (2006.01); A61P 25/28 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract
Provided are methods for treating a NAD comprising administering to a patient suffering from a NAD a composition comprising an eIF5A inhibitor compound in an amount effective to prevent intracellular hypusination of eIF5A, whereby gene expression of NMD-susceptible mRNA is increased.