The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 03, 2013

Filed:

Jul. 23, 1990
Applicants:

David Ginsburg, Ann Arbor, MI (US);

Stuart H. Orkin, Newton, MA (US);

Randal J. Kaufman, Boston, MA (US);

Inventors:

David Ginsburg, Ann Arbor, MI (US);

Stuart H. Orkin, Newton, MA (US);

Randal J. Kaufman, Boston, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/04 (2006.01); C12N 15/00 (2006.01); C12N 5/07 (2010.01); A61K 35/14 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Von Willebrand's Factor (VWF) is produced using an expression vector that includes: 1) a DNA sequence encoding a functional VWF protein; and 2) regulatory DNA capable of effecting expression of that DNA sequence in a host cell transformed with the vector. Restriction fragment length polymorphisms (RFLP's) associated with the VWF gene are identified and used in a probe for determining the source of a VWF gene in a DNA sample. The gene for VWF is localized to the short arm of human chromosome 12 (12p).


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