The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2013

Filed:

Dec. 29, 2010
Applicants:

Yanbin Liu, Acton, MA (US);

Nivedita Namdev, Westford, MA (US);

Rocio Palma, North Andover, MA (US);

Manish Tandon, Framingham, MA (US);

Jianqiang Wang, Acton, MA (US);

Hui Wu, Malden, MA (US);

Inventors:

Yanbin Liu, Acton, MA (US);

Nivedita Namdev, Westford, MA (US);

Rocio Palma, North Andover, MA (US);

Manish Tandon, Framingham, MA (US);

Jianqiang Wang, Acton, MA (US);

Hui Wu, Malden, MA (US);

Assignee:

ArQule, Inc., Woburn, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to substituted pyrrolo-aminopyrimidine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted pyrrolo-aminopyrimidine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. The substituted pyrrolo-aminopyrimidine compounds have the following general formula:


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