The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2013

Filed:

Sep. 01, 2010
Applicants:

Naoyuki Yamamoto, Sagamihara, JP;

Seiichi Mizuno, Machida, JP;

Takanobu Gotou, Machida, JP;

Keiichi Matsuura, Mitaka, JP;

Tadashi Shinoda, Sagamihara, JP;

Hideo Nishimura, Yosa-gun, JP;

Inventors:

Naoyuki Yamamoto, Sagamihara, JP;

Seiichi Mizuno, Machida, JP;

Shingo Nishimura, Sagamihara, JP;

Takanobu Gotou, Machida, JP;

Keiichi Matsuura, Mitaka, JP;

Tadashi Shinoda, Sagamihara, JP;

Assignee:

Calpis Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/00 (2006.01); C12N 9/62 (2006.01); A61K 38/00 (2006.01); A61K 38/05 (2006.01); A61K 38/06 (2006.01); C12N 9/50 (2006.01); C12N 9/48 (2006.01); A61K 47/00 (2006.01); A61K 38/55 (2006.01); A23C 9/12 (2006.01); C12P 21/06 (2006.01); A61P 9/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a casein hydrolysate containing free amino acids and in vivo indigestible peptides having minimally suppressed in vivo enzymatic digestibility, and expected to express functions, such as hypotensive effect, in living organism, and to a method for preparing such a hydrolysate, and use thereof. The casein hydrolysate of the present invention contains free amino acids and peptides, such as in vivo indigestible peptides including Xaa-Pro and Xaa-Pro-Pro, obtained by hydrolyzing animal milk casein to have an average chain length of not longer than 2.1 in terms of the number of amino acid residues, and has ACE inhibitory activity or hypotensive effect.


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