The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2013
Filed:
Apr. 13, 2012
Dirk Behrens, San Francisco, CA (US);
Elizabeth Bosch, San Francisco, CA (US);
Stephen K. Doberstein, San Francisco, CA (US);
Robert Forgan Halenbeck, San Francisco, CA (US);
Kevin Hestir, San Francisco, CA (US);
Min Mei Huang, San Francisco, CA (US);
Ernestine Lee, San Francisco, CA (US);
Haishan Lin, San Francisco, CA (US);
Thomas Linnemann, San Francisco, CA (US);
Shannon Marshall, San Francisco, CA (US);
Justin G. P. Wong, San Francisco, CA (US);
GE Wu, San Francisco, CA (US);
Aileen Zhou, San Francisco, CA (US);
Cindy Leo, San Francisco, CA (US);
Lewis T. Williams, San Francisco, CA (US);
Dirk Behrens, San Francisco, CA (US);
Elizabeth Bosch, San Francisco, CA (US);
Stephen K. Doberstein, San Francisco, CA (US);
Robert Forgan Halenbeck, San Francisco, CA (US);
Kevin Hestir, San Francisco, CA (US);
Min Mei Huang, San Francisco, CA (US);
Ernestine Lee, San Francisco, CA (US);
Haishan Lin, San Francisco, CA (US);
Thomas Linnemann, San Francisco, CA (US);
Shannon Marshall, San Francisco, CA (US);
Justin G. P. Wong, San Francisco, CA (US);
Ge Wu, San Francisco, CA (US);
Aileen Zhou, San Francisco, CA (US);
Cindy Leo, San Francisco, CA (US);
Lewis T. Williams, San Francisco, CA (US);
Five Prime Therapeutics, Inc., South San Francisco, CA (US);
Abstract
Disclosed is a newly identified secreted molecule, identified herein as 'monocyte, granulocyte, and dendritic cell colony stimulating factor' (MGD-CSF), the polypeptide sequence, and polynucleotides encoding the polypeptide sequence. Also provided is a procedure for producing the polypeptide by recombinant techniques employing, for example, vectors and host cells. Additionally, procedures are described to modify the disclosed novel molecules of the invention to prepare fusion molecules. Also disclosed are methods for using the polypeptides and active fragments thereof for treatment of a variety of diseases, including, for example, cancer, autoimmune and inflammatory diseases, infectious diseases, and recurrent pregnancy loss.