The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2013
Filed:
Jun. 18, 2009
Hideki Yoshioka, Takasaki, JP;
Shuhei Tsukamoto, Takasaki, JP;
Minoru Masuda, Takasaki, JP;
Reiko Machida, Takasaki, JP;
Yoshihiko Umegae, Takasaki, JP;
Masahiko Yabuuchi, Tokyo, JP;
Hideki Yoshioka, Takasaki, JP;
Shuhei Tsukamoto, Takasaki, JP;
Minoru Masuda, Takasaki, JP;
Reiko Machida, Takasaki, JP;
Yoshihiko Umegae, Takasaki, JP;
Masahiko Yabuuchi, Tokyo, JP;
Nippon Kayaku Kabushiki Kaisha, Tokyo, JP;
Abstract
A protein comprising an amino acid sequence having at least one mutation selected from a Gly-4 to Ala mutation, a Glu-6 to His mutation, a Ser-14 to Thr mutation, an Ala-37 to Thr or Arg mutation, a Pro-50 to Gln mutation, a Glu-67 to Gly mutation, an Asp-80 to Tyr mutation, a Val-93 to Met mutation, an Arg-156 to Pro mutation, a Leu-164 to Met mutation, an Asn-202 to Asp mutation, a Thr-235 to Ala mutation, an Asn-348 to Tyr mutation, a Gly-362 to Arg mutation and a Val-473 to Ala mutation in the amino acid sequence depicted in SEQ II NO:4. (2) A thermostable protein which comprises an amino acid sequence derived from the amino acid sequence having at least one variation described in (1) and having 1,5-anhydroglucitol dehydrogenase activity. These proteins act specifically on 1,5-anhydroglucitol (1,5-AG), have thermal stability and exhibit excellent storage stability.