The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2013

Filed:

Nov. 01, 2011
Applicants:

Mark A. Ashwell, Carlisle, MA (US);

Sudharshan Eathiraj, North Andover, MA (US);

Anton Filikov, Rockville, MD (US);

Steffi Koerner, Medford, MA (US);

Jean-marc Lapierre, Pelham, NH (US);

Yanbin Liu, Acton, MA (US);

Rocio Palma, North Andover, MA (US);

David Vensel, Brookline, MA (US);

Shin Iimura, Tokyo, JP;

Akiko Shiina, Tokyo, JP;

Kenichi Yoshida, Tokyo, JP;

Takanori Yamazaki, Tokyo, JP;

Akihisa Matsuda, Tokyo, JP;

Inventors:

Mark A. Ashwell, Carlisle, MA (US);

Sudharshan Eathiraj, North Andover, MA (US);

Anton Filikov, Rockville, MD (US);

Steffi Koerner, Medford, MA (US);

Jean-Marc Lapierre, Pelham, NH (US);

Yanbin Liu, Acton, MA (US);

Rocio Palma, North Andover, MA (US);

David Vensel, Brookline, MA (US);

Shin Iimura, Tokyo, JP;

Akiko Shiina, Tokyo, JP;

Kenichi Yoshida, Tokyo, JP;

Takanori Yamazaki, Tokyo, JP;

Akihisa Matsuda, Tokyo, JP;

Assignee:

ArQule, Inc., Woburn, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to substituted benzo[f]imidazo[1,2-d]pyrido[2,3-b][1,4]diazepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted benzo[f]imidazo[1,2-d]pyrido[2,3-b][1,4]diazepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.


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