The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 08, 2013
Filed:
Aug. 29, 2008
Mark T. Gladwin, Pittsburg, PA (US);
Daniel B. Kim-shapiro, Winston-Salem, NC (US);
Rakesh P. Patel, Hoover, AL (US);
Jeffrey Kerby, Birmingham, AL (US);
Mark T. Gladwin, Pittsburg, PA (US);
Daniel B. Kim-Shapiro, Winston-Salem, NC (US);
Rakesh P. Patel, Hoover, AL (US);
Jeffrey Kerby, Birmingham, AL (US);
The United States of America as represented by the Secretary of the Department of Health and Human Services, Washington, DC (US);
University of Alabama at Birmingham, Birmingham, AL (US);
Wake Forest University, Winston-Salem, NC (US);
Abstract
This disclosure relates to methods of using nitrite to detoxify stroma-free hemoglobin based blood substitutes. In particular, methods are described for using a blood substitute comprised of about equimolar amounts of nitrite and hemoglobin (e.g., nitrite-metHb) to treat, prevent, or ameliorate diseases of the blood in a subject, or as a blood replacement in a subject.