The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 2013

Filed:

Jan. 21, 2009
Applicants:

Matthew J. Bernett, Monrovia, CA (US);

Seung Yup Chu, Cypress, CA (US);

John R. Desjarlais, Pasadena, CA (US);

Sher Bahadur Karki, Pomona, CA (US);

Gregory Alan Lazar, Arcadia, CA (US);

Erik Weiking Pong, Temple City, CA (US);

Eugene Alexander Zhukovsky, Bethel, CT (US);

Inventors:

Matthew J. Bernett, Monrovia, CA (US);

Seung Yup Chu, Cypress, CA (US);

John R. Desjarlais, Pasadena, CA (US);

Sher Bahadur Karki, Pomona, CA (US);

Gregory Alan Lazar, Arcadia, CA (US);

Erik WeiKing Pong, Temple City, CA (US);

Eugene Alexander Zhukovsky, Bethel, CT (US);

Assignee:

Xencor, Inc., Monrovia, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention describes humanized antibodies that target CD40, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein the modification alters affinity to an FcγR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the antibodies of the invention.


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