The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2013

Filed:

May. 05, 2011
Applicants:

Adilah Bahadoor, Cambridge, MA (US);

Alfredo C. Castro, Winchester, MA (US);

Lawrence K. Chan, Brookline, MA (US);

Gregg F. Keaney, Lexington, MA (US);

Marta Nevalainen, Weymouth, MA (US);

Vesa Nevalainen, Weymouth, MA (US);

Stephane Peluso, Brookline, MA (US);

Daniel A. Snyder, Somerville, MA (US);

Thomas T. Tibbitts, Westford, MA (US);

Inventors:

Adilah Bahadoor, Cambridge, MA (US);

Alfredo C. Castro, Winchester, MA (US);

Lawrence K. Chan, Brookline, MA (US);

Gregg F. Keaney, Lexington, MA (US);

Marta Nevalainen, Weymouth, MA (US);

Vesa Nevalainen, Weymouth, MA (US);

Stephane Peluso, Brookline, MA (US);

Daniel A. Snyder, Somerville, MA (US);

Thomas T. Tibbitts, Westford, MA (US);

Assignee:

Infinity Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/41 (2006.01); C07D 249/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided herein are tetrazolone FASN inhibitors of the formula (I): or a pharmaceutically acceptable form thereof; wherein the variables R, Rand Rare defined herein. Also provided herein are pharmaceutical compositions of the compounds provided herein as well as methods of their use for the treatment of various disorders such as hyperproliferative disorders, inflammatory disorders, obesity-related disorders and microbial infections.


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