The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2013
Filed:
Sep. 29, 2010
Howard Glenn Damude, Hockessin, DE (US);
Peter John Gillies, Landenberg, PA (US);
Daniel Joseph Macool, Rutledge, PA (US);
Stephen K. Picataggio, Solana Beach, CA (US);
Dana M. Walters Pollak, West Chester, PA (US);
James John Ragghianti, Bear, DE (US);
Zhixiong Xue, Chadds Ford, PA (US);
Narendra S. Yadav, Wilmington, DE (US);
Hongxiang Zhang, Chadds Ford, PA (US);
Quinn Qun Zhu, West Chester, PA (US);
Howard Glenn Damude, Hockessin, DE (US);
Peter John Gillies, Landenberg, PA (US);
Daniel Joseph Macool, Rutledge, PA (US);
Stephen K. Picataggio, Solana Beach, CA (US);
Dana M. Walters Pollak, West Chester, PA (US);
James John Ragghianti, Bear, DE (US);
Zhixiong Xue, Chadds Ford, PA (US);
Narendra S. Yadav, Wilmington, DE (US);
Hongxiang Zhang, Chadds Ford, PA (US);
Quinn Qun Zhu, West Chester, PA (US);
E I du Pont de Nemours and Company, Wilmington, DE (US);
Abstract
Engineered strains of the oleaginous yeastcapable of producing greater than 25% eicosapentaenoic acid (EPA, an ω-3 polyunsaturated fatty acid) in the total oil fraction are described. These strains comprise various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprise various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of EPA. Production host cells are claimed, as are methods for producing EPA within said host cells.