The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2013
Filed:
Jun. 19, 2008
Neil Westlund, Groton, MA (US);
Jason Hill, Auburndale, MA (US);
Mark A. Ashwell, Carlisle, MA (US);
Nivedita Namdev, Westford, MA (US);
Jianqiang Wang, Acton, MA (US);
Syed Ali, North Andover, MA (US);
Neil Westlund, Groton, MA (US);
Jason Hill, Auburndale, MA (US);
Mark A. Ashwell, Carlisle, MA (US);
Nivedita Namdev, Westford, MA (US);
Jianqiang Wang, Acton, MA (US);
Syed Ali, North Andover, MA (US);
ArQule, Inc., Woburn, MA (US);
Abstract
The present invention relates to pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound or pyrrolidine-2,5-dione compound of the present invention. (Ia) (Ib) (IIa) (IIIb) Where U is independently selected from: (I) or (II) where U is independently selected from: