The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2013
Filed:
Jul. 01, 2008
Atsuhiro Abe, Minato-ku, JP;
Hideaki Shimizu, Minato-ku, JP;
Seigo Sawada, Minato-ku, JP;
Hiroshi Kodaira, Minato-ku, JP;
Atsuhiro Abe, Minato-ku, JP;
Hideaki Shimizu, Minato-ku, JP;
Seigo Sawada, Minato-ku, JP;
Hiroshi Kodaira, Minato-ku, JP;
Kabushiki Kaisha Yakult Honsha, Tokyo, JP;
Abstract
It is intended to provide a novel compound that has an excellent γ-secretase inhibitory effect and specifically inhibits Aβ production. The present invention provides a compound of the following formula (1) or a pharmaceutically acceptable salt thereof: wherein Rrepresents a linear or branched alkyl group having 1 to 4 carbon atoms or a phenyl group; Rrepresents a linear or branched alkyl group having 1 to 4 carbon atoms which may be substituted by one or more phenyl or halogenophenyl groups; Rrepresents a linear or branched alkyl group having 1 to 4 carbon atoms which may be substituted by one or more hydroxyl groups; Rrepresents a linear or branched alkyl group having 1 to 4 carbon atoms; and the symbol '*' represents a chiral center.