The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2013
Filed:
Jun. 09, 2008
Xin Wei Wang, Rockville, MD (US);
Junfang Ji, Clarksburg, VA (US);
Taro Yamashita, Ishikawa, JP;
Carlo M. Croce, Columbus, OH (US);
Xin Wei Wang, Rockville, MD (US);
Junfang Ji, Clarksburg, VA (US);
Taro Yamashita, Ishikawa, JP;
Carlo M. Croce, Columbus, OH (US);
Abstract
The invention provides a method of determining an HCC subtype in a subject comprising a) obtaining a sample from the subject, b) assaying the sample to detect the expression of 1 or more biomarkers, and c) correlating the expression of the biomarkers with an HCC subtype in a subject. The invention further provides methods of detecting HCC stem cells in a sample. Additionally, the invention provides methods and compositions for treating subjects with HCC that take advantage of the biomarkers associated with HCC stem cells.