The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2013
Filed:
Dec. 09, 2010
Ying Jiang, Eugene, OR (US);
Daniel J. Coleman, Corvallis, OR (US);
John J. Naleway, Eugene, OR (US);
Gabriele M. Cook, Eugene, OR (US);
Ying Jiang, Eugene, OR (US);
Daniel J. Coleman, Corvallis, OR (US);
John J. Naleway, Eugene, OR (US);
Gabriele M. Cook, Eugene, OR (US);
Marker Gene Technologies, Inc., Eugene, OR (US);
Abstract
A codon optimized and stabilized luciferase gene based upon the sequence of the natural luciferase gene isolated from(Japanese firefly) and a novel recombinant DNA characterized by incorporating this new gene coding for a novel luciferase into a vector DNA for improved activities in mammalian cells, are disclosed. This new luciferase exhibits long-wavelength light emission, as well as improved thermostability and higher expression levels in mammalian cell systems, compared to native luciferase. Assays using this new enzyme for measuring various biological metabolic functions are described.