The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2013
Filed:
Sep. 18, 2007
Matthew J. Bernett, Monrovia, CA (US);
John R. Desjarlais, Pasadena, CA (US);
Sher Bahadur Karki, Pomona, CA (US);
Gregory Alan Lazar, Arcadia, CA (US);
Umesh S. Muchhal, Monrovia, CA (US);
Duc-hanh Thi Nguyen, Sylmar, CA (US);
John O. Richards, Duarte, CA (US);
Matthew J. Bernett, Monrovia, CA (US);
John R. Desjarlais, Pasadena, CA (US);
Sher Bahadur Karki, Pomona, CA (US);
Gregory Alan Lazar, Arcadia, CA (US);
Umesh S. Muchhal, Monrovia, CA (US);
Duc-Hanh Thi Nguyen, Sylmar, CA (US);
John O. Richards, Duarte, CA (US);
Xencor, Inc., Monrovia, CA (US);
Abstract
The present disclosure describes antibodies that target HM1.24. In various aspects, the antibodies have specific CDR, variable, or full length sequences, have modifications with the parent antibody, or include at least one one modification relative to a parent antibody that alters affinity to an FcγR or alters effector function as compared to the parent antibody. Nucleic acids encoding the antibodies and methods of using the antibodies are also disclosed.