The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2013
Filed:
Aug. 19, 2008
Masao Kamahori, Kokubunji, JP;
Yu Ishige, Tokyo, JP;
Kotaro Yamashita, Mito, JP;
Yasuhisa Shibata, Hitachiomiya, JP;
Masafumi Miyake, Hitachinaka, JP;
Kuniaki Nagamine, Hachioji, JP;
Masao Kamahori, Kokubunji, JP;
Yu Ishige, Tokyo, JP;
Kotaro Yamashita, Mito, JP;
Yasuhisa Shibata, Hitachiomiya, JP;
Masafumi Miyake, Hitachinaka, JP;
Kuniaki Nagamine, Hachioji, JP;
Hitachi High-Technologies Corporation, Tokyo, JP;
Abstract
The present invention aims to simplify the structure and a fabrication method of an ion-selective electrode in an ion concentration measuring device that measures an anion, particularly a chloride ion, in a biological component. To this end, in a potential difference measuring unit, a quaternary ammonium salt derivative serving as a ligand for an anion is immobilized to the surface of a gold electrode by using as a linker an insulative molecule forming a self-assembled monolayer. The potential difference measuring unit measures an electromotive force generated with anion binding, as an interface potential change on the surface of the gold electrode. In order to reduce the influence of adsorption of impurities on the electrode surface, a high-molecular weight polymer is physically adsorbed on the gold electrode and thus used when a biological component is measured.