The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 26, 2013
Filed:
Sep. 14, 2009
Applicants:
Stuart H. Orkin, Brookline, MA (US);
Vijay G. Sankaran, Jamaica Plain, MA (US);
Inventors:
Stuart H. Orkin, Brookline, MA (US);
Vijay G. Sankaran, Jamaica Plain, MA (US);
Assignees:
Children's Medical Center Corporation, Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 5/071 (2006.01); C07H 21/02 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to methods and uses of modulating fetal hemoglobin expression (HbF) in a hematopoietic progenitor cells via inhibitors of BCL11A expression or activity, such as RNAi and antibodies.