The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2013

Filed:

Apr. 27, 2009
Applicants:

Jens Claus Munck Petersen, Århus C, DK;

Poul Nissen, Risskov, DK;

Peder Søndergaard Madsen, Risskov, DK;

Esben Meldgaard Høgh Quistgaard, Risskov, DK;

Morten Keller Grøftehauge, Århus C, DK;

Søren Skou Thirup, Risskov, DK;

Jacob Flyvholm Cramer, Århus V, DK;

Jacob Lauwring Andersen, Århus V, DK;

Inventors:

Jens Claus Munck Petersen, Århus C, DK;

Poul Nissen, Risskov, DK;

Peder Søndergaard Madsen, Risskov, DK;

Esben Meldgaard Høgh Quistgaard, Risskov, DK;

Morten Keller Grøftehauge, Århus C, DK;

Søren Skou Thirup, Risskov, DK;

Jacob Flyvholm Cramer, Århus V, DK;

Jacob Lauwring Andersen, Århus V, DK;

Assignee:

H. Lundbeck A/S, Valby, DK;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a Sortilin crystal and methods for growing said crystal. The invention furthermore provide methods for design of specific ligands based on the crystal structure of Sortilin. The present invention also relates to the preparation and use of such ligands for the preparation of a medicament for the treatment of disease, damage or disorders of the central and peripheral nervous systems.


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