The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 12, 2013

Filed:

Nov. 03, 2004
Applicants:

Timothy W. Abraham, Minnetonka, MN (US);

Douglas C. Cameron, Plymouth, MN (US);

Paula M. Hicks, Eden Prairie, MN (US);

Sara C. Mcfarlan, St. Paul, MN (US);

John Rosazza, Iowa City, IA (US);

Lishan Zhao, Carlsbad, CA (US);

David P. Weiner, Del Mar, CA (US);

Inventors:

Timothy W. Abraham, Minnetonka, MN (US);

Douglas C. Cameron, Plymouth, MN (US);

Paula M. Hicks, Eden Prairie, MN (US);

Sara C. McFarlan, St. Paul, MN (US);

John Rosazza, Iowa City, IA (US);

Lishan Zhao, Carlsbad, CA (US);

David P. Weiner, Del Mar, CA (US);

Assignee:

Cargill, Incorporated, Wayzata, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/18 (2006.01); C12P 13/22 (2006.01); C12P 21/06 (2006.01); C07H 21/04 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods and compositions that can be used to make monatin from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided. Methods are also disclosed for producing the indole-3-pyruvate and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid intermediates. Compositions provided include nucleic acid molecules, polypeptides, chemical structures, and cells. Methods include in vitro and in vivo processes, and the in vitro methods include chemical reactions.


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