The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2013
Filed:
Oct. 26, 2009
Applicants:
Albee Messing, Madison, WI (US);
Woosung Cho, Madison, WI (US);
Jon Scott Thorson, Middleton, WI (US);
Randal D. Goff, Madison, WI (US);
Inventors:
Albee Messing, Madison, WI (US);
Woosung Cho, Madison, WI (US);
Jon Scott Thorson, Middleton, WI (US);
Randal D. Goff, Madison, WI (US);
Assignee:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 31/715 (2006.01); A61K 31/675 (2006.01); A61K 31/66 (2006.01); A61K 31/59 (2006.01);
U.S. Cl.
CPC ...
Abstract
Provided herein are methods of decreasing glial fibrillary acidic protein (GFAP) levels in a cell. Such methods include administering an effective amount of a GFAP lowering compound to the cell. Also provided are compounds useful for the treatment of Alexander disease in subjects at risk of or diagnosed with Alexander disease and methods for the identification of such compounds.