The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2013
Filed:
Jun. 25, 2009
Mitsuhiro Kishino, Saga, JP;
Toshimichi Kamei, Kawasaki, JP;
Mitsuhiro Kishino, Saga, JP;
Toshimichi Kamei, Kawasaki, JP;
Ajinomoto Co., Inc., Tokyo, JP;
Abstract
The present invention provides a method for separating and obtaining a basic amino acid hydrochloride from a basic amino acid fermentation broth or an enzyme reaction solution which enzyme reaction is catalyzed by viable microbial cells which are able to produce a basic amino acid, each containing sulfate ions, wherein product yields and qualities are almost the same and are secured more easily, as compared with the conventional technique. The method may include the steps of adding a metal chloride such as calcium chloride, potassium chloride, magnesium chloride, and barium chloride to the basic amino acid fermentation broth or the enzyme reaction solution containing sulfate ions to precipitate the sulfate ions as crystals of the resulting metal sulfate, (2) removing the metal sulfate crystals from the basic amino acid solution, (3) cooling the basic amino acid fermentation broth or the enzyme reaction solution from which the metal sulfate crystals have been removed while maintaining the concentration of the metal sulfate below its saturation concentration, resulting in precipitatation the basic amino acid as hydrochloride crystals, and (4) separating and collecting the basic amino acid hydrochloride crystals.