The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2012

Filed:

May. 23, 2010
Applicants:

Romulus Kimbro Brazzell, Morrisville, NC (US);

Peter Anthony Campochiaro, Baltimore, MD (US);

Katharine Hilary Dixon, Olney, MD (US);

Michael Kaleko, Rockville, MD (US);

Tianci Luo, Clarksville, MD (US);

Inventors:

Romulus Kimbro Brazzell, Morrisville, NC (US);

Peter Anthony Campochiaro, Baltimore, MD (US);

Katharine Hilary Dixon, Olney, MD (US);

Michael Kaleko, Rockville, MD (US);

Tianci Luo, Clarksville, MD (US);

Assignee:

Novartis AG, Basel, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods are provided for the treatment of ocular neovascularization by increasing, in an individual afflicted with ocular neovascularization, in vivo concentrations of an endostatin protein in the ocular tissues of the individual to an ocular neovascularization inhibiting effective amount, where the endostatin protein has anti-ocular neovascularization activity in vivo.


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