The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 2012

Filed:

Apr. 21, 2008
Applicants:

Masao Kamahori, Kokubunji, JP;

Yu Ishige, Tokyo, JP;

Kotaro Yamashita, Mito, JP;

Yasuhisa Shibata, Hitachiomiya, JP;

Masafumi Miyake, Hitachinaka, JP;

Inventors:

Masao Kamahori, Kokubunji, JP;

Yu Ishige, Tokyo, JP;

Kotaro Yamashita, Mito, JP;

Yasuhisa Shibata, Hitachiomiya, JP;

Masafumi Miyake, Hitachinaka, JP;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 27/333 (2006.01);
U.S. Cl.
CPC ...
Abstract

A crown ether derivative that acts as cation capturing ligand and alkanethiol having a longer carbon chain than a linker are immobilized, coexisting together, on the surface of a gold electrode, by using as the linker an insulating molecule (e.g., alkanethiol) that forms self-assembled monolayers. Electromotive force produced in association with cation coordination is measured by a potentiometer through a change in interfacial potential on the surface of the gold electrode. Further, an insulated gate field effect transistor formed on the same substrate as the gold electrode is used as the potentiometer. Furthermore, a straight-chain polymer physically adsorbed on the gold electrode is used in order to reduce the influence of the adsorption of impurities on the surface of the electrode during biological sample measurement.


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