The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 25, 2012

Filed:

Dec. 30, 2009
Applicants:

Syed M. Ali, North Andover, MA (US);

Mark A. Ashwell, Carlisle, MA (US);

Jason Hill, Auburndale, MA (US);

Jean-marc Lapierre, Pelham, NH (US);

Magdi Moussa, Malden, MA (US);

Nivedita Namdev, Westford, MA (US);

Robert Nicewonger, Tyngsboro, MA (US);

Manish Tandon, Framingham, MA (US);

Rui-yang Yang, Lexington, MA (US);

Inventors:

Syed M. Ali, North Andover, MA (US);

Mark A. Ashwell, Carlisle, MA (US);

Jason Hill, Auburndale, MA (US);

Jean-Marc Lapierre, Pelham, NH (US);

Magdi Moussa, Malden, MA (US);

Nivedita Namdev, Westford, MA (US);

Robert Nicewonger, Tyngsboro, MA (US);

Manish Tandon, Framingham, MA (US);

Rui-Yang Yang, Lexington, MA (US);

Assignee:

ArQule, Inc., Woburn, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/90 (2006.01); A61K 31/519 (2006.01); C07D 487/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to substituted 1H-pyrazolo-[3,4-d]pyrimidine-6-amine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted 1H-pyrazolo-[3,4-d]pyrimidine-6-amine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.


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