The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2012
Filed:
Oct. 18, 2004
Hsueh-chia Chang, Notre Dame, IN (US);
Shau-chun (Paul) Wang, Notre Dame, IN (US);
Dmitri Lastochkin, Notre Dame, IN (US);
Leslie Yeo, Notre Dame, IN (US);
Zachary Gagnon, Notre Dame, IN (US);
Siddharth Maheshwari, Notre Dame, IN (US);
Hsueh-Chia Chang, Notre Dame, IN (US);
Shau-Chun (Paul) Wang, Notre Dame, IN (US);
Dmitri Lastochkin, Notre Dame, IN (US);
Leslie Yeo, Notre Dame, IN (US);
Zachary Gagnon, Notre Dame, IN (US);
Siddharth Maheshwari, Notre Dame, IN (US);
University of Notre Dame du Lac, Notre Dame, IN (US);
Abstract
The present invention provides an electrospray device using a high frequency alternating current (AC) above 10 kHz to generate fine micron sized drops. The apparatus generally functions by applying a high frequency alternating current electric field across one or more micro-needles and one or more conducting elements. The present invention may be used to generate aerosol drops for respiratory drug delivery or as a microencapsulation technique for the encapsulation of drugs, DNA, protein, osteogenic or dermatological growth factors, bacteria, viruses, immobilized enzyme receptors and fluorescent particles for controlled release drug delivery, tissue or bone engineering, clinical or environmental field testing and as biosensors for clinical or drug monitoring. In addition, the present invention may be used to synthesize biodegradable fibers as bioscaffolds for tissue engineering, surgical sutures or medical gauze that enhance blood coagulation, and further may be encapsulated by other agents.