The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 31, 2012

Filed:

Jun. 19, 2008
Applicants:

Jifeng Liu, Winchester, MA (US);

Syed M. Ali, North Andover, MA (US);

Mark A. Ashwell, Carlisle, MA (US);

Ping YE, Lexington, MA (US);

Yousheng Guan, North Billerica, MA (US);

Shi-chung NG, San Diego, CA (US);

Rocio Palma, North Andover, MA (US);

Dan Yohannes, Cambridge, MA (US);

Inventors:

Jifeng Liu, Winchester, MA (US);

Syed M. Ali, North Andover, MA (US);

Mark A. Ashwell, Carlisle, MA (US);

Ping Ye, Lexington, MA (US);

Yousheng Guan, North Billerica, MA (US);

Shi-Chung Ng, San Diego, CA (US);

Rocio Palma, North Andover, MA (US);

Dan Yohannes, Cambridge, MA (US);

Assignee:

ArQule, Inc., Woburn, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); A61K 31/517 (2006.01); C07D 401/00 (2006.01); C07D 403/00 (2006.01); C07D 413/00 (2006.01); C07D 417/00 (2006.01); C07D 419/00 (2006.01); C07D 239/72 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to quinazolinone compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising the quinazolinone compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a quinazolinone compound of the present invention.


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