The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2012

Filed:

Oct. 07, 2010
Applicants:

Donald C. Foster, Lake Forest Park, WA (US);

Wenfeng Xu, Seattle, WA (US);

Karen L. Madden, Bellevue, WA (US);

James D. Kelly, Mercer Island, WA (US);

Cindy A. Sprecher, Patagonia, AZ (US);

Cameron S. Brandt, Seattle, WA (US);

Mark W. Rixon, Issaquah, WA (US);

Scott R. Presnell, Tacoma, WA (US);

Brian A. Fox, Seattle, WA (US);

Inventors:

Donald C. Foster, Lake Forest Park, WA (US);

Wenfeng Xu, Seattle, WA (US);

Karen L. Madden, Bellevue, WA (US);

James D. Kelly, Mercer Island, WA (US);

Cindy A. Sprecher, Patagonia, AZ (US);

Cameron S. Brandt, Seattle, WA (US);

Mark W. Rixon, Issaquah, WA (US);

Scott R. Presnell, Tacoma, WA (US);

Brian A. Fox, Seattle, WA (US);

Assignee:

ZymoGenetics, Inc., Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/03 (2006.01); A61K 45/00 (2006.01); C07K 14/54 (2006.01); C12P 21/02 (2006.01); A61P 17/00 (2006.01); C12N 15/09 (2006.01); C12N 5/07 (2010.01);
U.S. Cl.
CPC ...
Abstract

A soluble receptor to IL-20 having two polypeptide subunits, IL-20RA (formerly called ZcytoR7) and IL-20RB (formerly called DIRS1). The two subunits are preferably linked together. In one embodiment one subunit is fused to the constant region of the light chain of an immunoglobulin, and the other subunit is fused to the constant region of the heavy chain of the immunoglobulin. The light chain and the heavy chain are connected via a disulfide bond.


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