The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2012
Filed:
Feb. 01, 2011
Peter A. Carr, Medford, MA (US);
Brian Y. Chow, Cambridge, MA (US);
Joseph M. Jacobson, Newton, MA (US);
David W. Mosley, Cambridge, MA (US);
Christopher Emig, Napa, CA (US);
Peter A. Carr, Medford, MA (US);
Brian Y. Chow, Cambridge, MA (US);
Joseph M. Jacobson, Newton, MA (US);
David W. Mosley, Cambridge, MA (US);
Christopher Emig, Napa, CA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
In a method for synthesizing a long nucleic acid molecule, a first immobilized nucleic acid has a first 5' region and a first 3′ region and a second immobilized nucleic acid has a second 5′ region and a second 3′ region. The second 3′ region and the first 5′ region have identical nucleic acid sequences. An oligonucleotide is hybridized to the first 3′ region, extending the hybridized oligonucleotide and producing a first extension product having a 3′ region that is complementary to the first 5′ region. The 3′ region of the first extension product is hybridized to the second 3′ region, extending the 3′ region of the first extension product and producing a synthesized nucleic acid molecule having a 3′ region that is complementary to the second 5′ region, wherein the synthesized nucleic acid molecule has a sequence complementary to the first and second 3′ and 5′ regions.