The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 15, 2012

Filed:

Jun. 12, 2008
Applicants:

Badry Bursulaya, San Diego, CA (US);

Dai Cheng, San Diego, CA (US);

Jiqing Jiang, San Diego, CA (US);

Donald S. Karanewsky, Escondido, CA (US);

Yi Liu, San Diego, CA (US);

Shifeng Pan, San Diego, CA (US);

Yongqin Wan, Irvine, CA (US);

Xia Wang, San Diego, CA (US);

Yun Feng Xie, San Diego, CA (US);

Yang Yang, San Diego, CA (US);

Inventors:

Badry Bursulaya, San Diego, CA (US);

Dai Cheng, San Diego, CA (US);

Jiqing Jiang, San Diego, CA (US);

Donald S. Karanewsky, Escondido, CA (US);

Yi Liu, San Diego, CA (US);

Shifeng Pan, San Diego, CA (US);

Yongqin Wan, Irvine, CA (US);

Xia Wang, San Diego, CA (US);

Yun Feng Xie, San Diego, CA (US);

Yang Yang, San Diego, CA (US);

Assignee:

IRM LLC, Hamilton, BM;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/02 (2006.01); C07D 413/14 (2006.01); A61K 31/536 (2006.01); A61K 31/551 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a novel class of compounds of formula (I), pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or dysregulated B cell activities, particularly diseases or disorders that involve aberrant activation of inositol 1,4,5-trisphosphate 3-kinase B (ITPKb).


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