The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 08, 2012

Filed:

Mar. 18, 2009
Applicants:

Xia LI, Havertown, PA (US);

Weihua LI, Broomall, PA (US);

Danielle R. Reed, Glenside, PA (US);

Alexander A. Bachmanov, Philadelphia, PA (US);

Joseph G. Brand, Wayne, PA (US);

Inventors:

Xia Li, Havertown, PA (US);

Weihua Li, Broomall, PA (US);

Danielle R. Reed, Glenside, PA (US);

Alexander A. Bachmanov, Philadelphia, PA (US);

Joseph G. Brand, Wayne, PA (US);

Assignee:

Monell Chemical Senses Center, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); C07K 19/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to the discovery of several genes of the domestic cat () associated with taste perception. The invention provides, inter alia, the nucleotide sequence of the feline Tas1r1, Tas1r2, and Tas1r3 receptor genes, the amino acid sequences of the polypeptides encoded thereby, and antibodies to the polypeptides. The present invention also relates to methods for screening for compounds that modify the genes' function or activity, the compounds identified by such screens, and mimetics of the identified compounds. The invention further provides methods for modifying the taste preferences, ingestive responses, or general behavior of a mammal, such as a cat, by administering compounds that affect the function or activity of the gene or the polypeptide encoded thereby.


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